Adolescence and puberty by John Bancroft; June Machover Reinisch

By John Bancroft; June Machover Reinisch

Scientists from 10 disciplines give a contribution essays which discover quite a few points of this serious degree in human improvement, in a quantity designed for the good thing about social and developmental psychologists, psychologists drawn to sexuality reviews, and baby and adolescent psychiatrists.

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Although investigators have wondered whether adrenarche could play a role in triggering the onset of hypothalamicpituitary-gonadal maturation, clinical observations in children with adrenal insufficiency have not supported this concept (Cutler & Loriaux, 1980). , 1985). , 1982). , 1983), but in children more discordance is Human Puberty: Biological and Environmental Factors 33 Figure 2-3. Serial gonadotropin responses to intravenous GnRH in a boy with isolated GH deficiency. Abbreviations as in Figure 2-2.

There is some evidence for a neuronal system in the posterior hypothalamus that holds GnRH neuronal activity in check, but the nature of this system has not been char- 24 Biological and Environmental Factors acterized. Signals that may provide a stimulatory cue for puberty onset include attainment of a critical body weight, body composition, basal metabolic rate, or stimulatory metabolic milieu. Although there are ample clinical data showing correlations between these factors and puberty onset, few experiments addressing whether such factors actually play a causal role in the pubertal increase in GnRH secretion have been performed.

7-45). New York: Academic Press. Haymond, M. , Karl, I. , Clarke, W. , Pagliara, A. , & Santiago, J. C. (1982). Differences in circulating gluconeogenic substrates during shortterm fasting in men, women, and children. Metabolism, 31, 33-42. Jakacki, R. , Kelch, R. , Sauder, S. , Lloyd, J. , Hopwood, N. , & Marshall, J. C. (1982). Pulsatile secretion of luteinizing hormone in children. Journal of Clinical Endocrinology and Metabolism, 55, 453-458. , Boyar, R. , Finkelstein, J. , & Weitzman, E. D.

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